Deatsetilvindolin - Deacetylvindoline

Deatsetilvindolin
Ismlar
	IUPAC nomi Metil (2β, 3β, 4β, 5a, 12β, 19a) -3,4-dihidroksi-16-metoksi-1-metil-6,7-dihidroaspidospermidin-3-karboksilat
	Boshqa ismlar Desatsetilvindolin; 17-O-Datsetilvindolin
Identifikatorlar
CAS raqami	3633-92-9;
3D model (JSmol )	Interaktiv rasm;
ChEBI	CHEBI: 18362;
ChemSpider	228679;
PubChem CID	260534;
	InChI InChI = 1S / C23H30N2O5 / c1-5-21-9-6-11-25-12-10-22 (17 (21) 25) 15-8-7-14 (29-3) 13-16 (15) 24 (2) 18 (22) 23 (28,19 (21) 26) 20 (27) 30-4 / h6-9,13,17-19,26,28H, 5,10-12H2,1-4H3 / t17-, 18 +, 19 +, 21 +, 22 +, 23- / m0 / s1 Kalit: ZDKMPOJNYNVYLA-PEGGBQQISA-N; InChI = 1 / C23H30N2O5 / c1-5-21-9-6-11-25-12-10-22 (17 (21) 25) 15-8-7-14 (29-3) 13-16 (15) 24 (2) 18 (22) 23 (28,19 (21) 26) 20 (27) 30-4 / h6-9,13,17-19,26,28H, 5,10-12H2,1-4H3 / t17-, 18 +, 19 +, 21 +, 22 +, 23- / m0 / s1 Kalit: ZDKMPOJNYNVYLA-PEGGBQQIBO;
	Jilmayganlar CC [C @@] 12C = CCN3 [C @@ H] 1 [C @@] 4 (CC3) c5ccc (cc5N ([C @ H] 4 [C @] ([C @@ H] 2O) (C (= O) OC) O) C) OC;
Xususiyatlari
Kimyoviy formulalar	C23H30N2O5
Molyar massa	414.502 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	Infobox ma'lumotnomalari

Deatsetilvindolin tomonidan ishlab chiqarilgan terpen indol alkaloididir Catararanthus roseus. Deatsetilvindolin - ning gidroksillanishining hosilasi desatsetoksivindolin tomonidan deatsetoksivindolin 4-gidroksilaza (D4H).^[1] Bu substrat deatsetilvindolin O-atsetiltransferaza (DAT) qaysi atsetilatlar a gidroksi guruhi shakllantirmoq vindolin, farmatsezial jihatdan qimmat bisindol alkaloidini hosil qilish uchun ikkita tezkor kashshoflardan biri vinblastin.^[2]

Adabiyotlar

^ Vazkes-Flota, De Kerolis, Alarko va De Luka (1997) Katsantus Rusus (L.) G. Don tarkibidagi vindolin biosintezida ishtirok etgan 2-oksoglutarat qaram-dioksigenaza, desatsetoksivindolin-4-gidroksilaza molekulyar klonlash va tavsifi. O'simliklar molekulyar biologiyasi. 34 (6). 935-948
^ Power, Kurz and De Luca (1990) Atsetilkoenzim A ning tozalanishi va xarakteristikasi: Katarantus rousidan deatsetilvindolin 4-O-asetiltransferaza. Biokimyo va biofizika arxivlari. 279 (2). 370-376

Ismlar

IUPAC nomi Metil (2β, 3β, 4β, 5a, 12β, 19a) -3,4-dihidroksi-16-metoksi-1-metil-6,7-dihidroaspidospermidin-3-karboksilat
Boshqa ismlar Desatsetilvindolin; 17-O-Datsetilvindolin
Identifikatorlar
CAS raqami	3633-92-9
3D model (JSmol )	Interaktiv rasm
ChEBI	CHEBI: 18362
ChemSpider	228679
PubChem CID	260534
InChI InChI = 1S / C23H30N2O5 / c1-5-21-9-6-11-25-12-10-22 (17 (21) 25) 15-8-7-14 (29-3) 13-16 (15) 24 (2) 18 (22) 23 (28,19 (21) 26) 20 (27) 30-4 / h6-9,13,17-19,26,28H, 5,10-12H2,1-4H3 / t17-, 18 +, 19 +, 21 +, 22 +, 23- / m0 / s1 Kalit: ZDKMPOJNYNVYLA-PEGGBQQISA-N InChI = 1 / C23H30N2O5 / c1-5-21-9-6-11-25-12-10-22 (17 (21) 25) 15-8-7-14 (29-3) 13-16 (15) 24 (2) 18 (22) 23 (28,19 (21) 26) 20 (27) 30-4 / h6-9,13,17-19,26,28H, 5,10-12H2,1-4H3 / t17-, 18 +, 19 +, 21 +, 22 +, 23- / m0 / s1 Kalit: ZDKMPOJNYNVYLA-PEGGBQQIBO
Jilmayganlar CC [C @@] 12C = CCN3 [C @@ H] 1 [C @@] 4 (CC3) c5ccc (cc5N ([C @ H] 4 [C @] ([C @@ H] 2O) (C (= O) OC) O) C) OC
Xususiyatlari
Kimyoviy formulalar	C₂₃H₃₀N₂O₅
Molyar massa	414.502 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari