Desatsetoksivindolin - Desacetoxyvindoline

Desatsetoksivindolin
Ismlar
	IUPAC nomi Metil (2β, 3β, 5a, 12β, 19a) -3-gidroksi-16-metoksi-1-metil-6,7-didehidroaspidospermidin-3-karboksilat
	Boshqa ismlar Deatsetoksivindolin
Identifikatorlar
3D model (JSmol )	Interaktiv rasm;
ChemSpider	388838;
PubChem CID	439783;
	InChI InChI = 1S / C23H30N2O4 / c1-5-21-9-6-11-25-12-10-22 (18 (21) 25) 16-8-7-15 (28-3) 13-17 (16) 24 (2) 19 (22) 23 (27,14-21) 20 (26) 29-4 / h6-9,13,18-19,27H, 5,10-12,14H2,1-4H3 / t18- , 19 +, 21-, 22 +, 23 + / m0 / s1 Kalit: WNKDGPXNFMMOEJ-RNJSZURPSA-N; InChI = 1 / C23H30N2O4 / c1-5-21-9-6-11-25-12-10-22 (18 (21) 25) 16-8-7-15 (28-3) 13-17 (16) 24 (2) 19 (22) 23 (27,14-21) 20 (26) 29-4 / h6-9,13,18-19,27H, 5,10-12,14H2,1-4H3 / t18- , 19 +, 21-, 22 +, 23 + / m0 / s1 Kalit: WNKDGPXNFMMOEJ-RNJSZURPBV;
	Jilmayganlar CC [C @] 12C [C @@] ([C @ H] 3 [C @@] 4 ([C @ H] 1N (CC4) CC = C2) c5ccc (cc5N3C) OC) (C (= O) OC) O;
Xususiyatlari
Kimyoviy formulalar	C23H30N2O4
Molyar massa	398.503 g · mol−1
	Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
	Infobox ma'lumotnomalari

Desatsetoksivindolin o'simlik tomonidan ishlab chiqarilgan terpen idol alkaloididir Catararanthus roseus. Desatsetoksivindolin - bu metillanish natijasida hosil bo'lgan mahsulot azot ustida indol ferment tomonidan halqa 3-gidroksi-16-metoksi-2,3-dihidrotabersonin N-metiltransferaza (NMT).^[1] Metabolit - bu substrat desatsetoksivindolin 4-gidroksilaza Hosil bo'lish uchun gidroksillanishni katalizlovchi (D4H) deatsetilvindolin.^[2]

Adabiyotlar

^ Liscombe, Usera and O'connor (2010) Tokoferol S metiltransferazlarining homologi antikanser alkaloid biosintezida N metillanishini katalizlaydi. Milliy fanlar akademiyasi materiallari. 107 (44). 18793-18798
^ Vazkes-Flota, De Kerolis, Alarko va De Luka (1997) Katsantus Rusus (L.) G. Don tarkibidagi vindolin biosintezida ishtirok etgan 2-oksoglutarat qaram-dioksigenaza, desatsetoksivindolin-4-gidroksilaza molekulyar klonlash va tavsifi. O'simliklar molekulyar biologiyasi. 34 (6). 935-948

Ismlar

IUPAC nomi Metil (2β, 3β, 5a, 12β, 19a) -3-gidroksi-16-metoksi-1-metil-6,7-didehidroaspidospermidin-3-karboksilat
Boshqa ismlar Deatsetoksivindolin
Identifikatorlar
3D model (JSmol )	Interaktiv rasm
ChemSpider	388838
PubChem CID	439783
InChI InChI = 1S / C23H30N2O4 / c1-5-21-9-6-11-25-12-10-22 (18 (21) 25) 16-8-7-15 (28-3) 13-17 (16) 24 (2) 19 (22) 23 (27,14-21) 20 (26) 29-4 / h6-9,13,18-19,27H, 5,10-12,14H2,1-4H3 / t18- , 19 +, 21-, 22 +, 23 + / m0 / s1 Kalit: WNKDGPXNFMMOEJ-RNJSZURPSA-N InChI = 1 / C23H30N2O4 / c1-5-21-9-6-11-25-12-10-22 (18 (21) 25) 16-8-7-15 (28-3) 13-17 (16) 24 (2) 19 (22) 23 (27,14-21) 20 (26) 29-4 / h6-9,13,18-19,27H, 5,10-12,14H2,1-4H3 / t18- , 19 +, 21-, 22 +, 23 + / m0 / s1 Kalit: WNKDGPXNFMMOEJ-RNJSZURPBV
Jilmayganlar CC [C @] 12C [C @@] ([C @ H] 3 [C @@] 4 ([C @ H] 1N (CC4) CC = C2) c5ccc (cc5N3C) OC) (C (= O) OC) O
Xususiyatlari
Kimyoviy formulalar	C₂₃H₃₀N₂O₄
Molyar massa	398.503 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar keltirilgan standart holat (25 ° C [77 ° F], 100 kPa da).
Infobox ma'lumotnomalari